Preliminary study on bulbocavernosus reflex in male patients with Parkinson's disease

doi:10.3877/cma.j.issn.1674-0785.2023.01.004

Abstract

Abstract:

Objective

To preliminarily investigate the manifestations of bulbocavernosus reflex (BCR) in men with Parkinson's disease (PD), in order to provide clues for the diagnosis of PD.

Methods

Thirteen male PD patients treated at the Department of Neurology, Peking University International Hospital were collected from November 2020 to January 2022, and the clinical features, BCR, and pudendal nerve somatosensory evoked potential (PSEP) manifestations in PD patients were analyzed, and the data were compared with those in 9 men who received health check-up.

Results

The age of subjects in the PD group and the control group was (70.1±10.9) years and (59.6±13.0) years, respectively, and the height was (166.8±4.8) cm and (165.7±4.5) cm, respectively (P＞0.05 for both). Eleven cases (84.6%) of PD patients had constipation, 9 (69.2%) had urinary dysfunction, and 11 (84.6%) had erectile dysfunction. The elicitation rate of BCR in the PD group was 69.2% (9/13) and it was 100% in the control group, and the difference was statistically significant (P＜0.05). There was no significant difference in the latency of BCR between the PD and the control group [(38.3±4.5) ms vs (36.2±3.8) ms, P＞0.05]; the amplitude of BCR in the PD group was lower than that in the control group [(113±96) uV vs (1255±309) uV], and the difference was statistically significant (P＜0.05). There was no significant difference in PSEP latency or amplitude between the two groups (P＞0.05 for both).

Conclusion

The sacral spinal reflex arc is injured in male PD patients, and BCR may be helpful in the diagnosis of PD.

Key words: Parkinson's disease, Bulbocavernosus reflex, Reflex arc, Pudendal nerve somatosensory evoked potential, Diagnosis

Tuanfeng Yang, Xue Meng, Yanxiang Wang, Jia Lu, Desheng Kong, Yuanli Zhao, Xianzeng Liu. Preliminary study on bulbocavernosus reflex in male patients with Parkinson's disease[J]. Chinese Journal of Clinicians(Electronic Edition), 2023, 17(01): 28-32.

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URL: https://zhlcyszz.cma-cmc.com.cn/EN/10.3877/cma.j.issn.1674-0785.2023.01.004

https://zhlcyszz.cma-cmc.com.cn/EN/Y2023/V17/I01/28

Figures/Tables 3

References 28

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例序	年龄（岁）	身高（cm）	病程（年）	Hoehn-Yahr分级	便秘	泌尿功能障碍	勃起功能障碍	体位性低血压
1	40	172	1.5	1.0	无	无	无	无
2	79	166	2.0	2.5	有	有	有	无
3	78	159	4.0	4.0	有	有	有	无
4	67	167	1.0	3.0	有	有	有	无
5	79	162	0.5	2.0	有	有	有	无
6	65	164	1.0	2.0	有	有	有	无
7	64	168	1.0	2.0	有	无	有	无
8	81	173	3.0	2.5	有	有	有	有
9	70	163	4.0	3.0	有	有	有	无
10	69	173	1.0	1.0	有	有	有	有
11	77	167	2.0	2.0	有	无	有	无
12	66	173	1.0	3.0	无	无	无	无
13	76	162	3.0	3.0	有	有	有	有

例序	年龄（岁）	身高（cm）	病程（年）	Hoehn-Yahr分级	便秘	泌尿功能障碍	勃起功能障碍	体位性低血压
1	40	172	1.5	1.0	无	无	无	无
2	79	166	2.0	2.5	有	有	有	无
3	78	159	4.0	4.0	有	有	有	无
4	67	167	1.0	3.0	有	有	有	无
5	79	162	0.5	2.0	有	有	有	无
6	65	164	1.0	2.0	有	有	有	无
7	64	168	1.0	2.0	有	无	有	无
8	81	173	3.0	2.5	有	有	有	有
9	70	163	4.0	3.0	有	有	有	无
10	69	173	1.0	1.0	有	有	有	有
11	77	167	2.0	2.0	有	无	有	无
12	66	173	1.0	3.0	无	无	无	无
13	76	162	3.0	3.0	有	有	有	有

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